Synthesis and Characterization of Graphene Quantum Dots from Nutmeg Seeds and its Biomedical Application
Anooj E. S1, Praseetha P. K2

1Anooj E. S, Department of Nanotechnology, Noorul Islam Centre for Higher Education, Kumaracoil, Thuckalay (Tamil Nadu),  India.
2Praseetha P. K, Department of Nanotechnology, Noorul Islam Centre for Higher Education, Kumaracoil, Thuckalay (Tamil Nadu),  India.
Manuscript received on 02 May 2019 | Revised Manuscript received on 14 May 2019 | Manuscript Published on 23 May 2019 | PP: 144-151 | Volume-7 Issue-6S5 April 2019 | Retrieval Number: F10220476S519/2019©BEIESP
Open Access | Editorial and Publishing Policies | Cite | Mendeley | Indexing and Abstracting
© The Authors. Blue Eyes Intelligence Engineering and Sciences Publication (BEIESP). This is an open access article under the CC-BY-NC-ND license (

Abstract: The present investigation was suggested to the synthesis of graphene quantum dots using Nutmeg seed by green synthesis and hydrothermal method. The structure and morphology of ensuring the product would have represented by UV, FTIR, X-ray Diffraction (PXRD), TEM and SAED pattern. Then anti-microbial, anti-oxidant and anti-cancer activity, MIC (Minimum Inhibition Concentration) and phytotoxicity of Nutmeg seeds mediated graphene quantum dots were analyzed. The formation of GQDs are confirmed using the noticeable UV absorption peaks 320nm, XRD pattern shows the average crystallite size of the GQDs is 6.1nm, TEM results revealed most of the particle size possessed spherical shapes with an average particle size range of 7.2 nm. CSE-GQDs (Nutmeg seed extract-Graphene quantum dots) showed greatest antimicrobial activity against several bacteria species such as Staphylococcus aureus, Pseudomonas aeroginosa, Streptococcus mutans, Salmonella sp, Escherichia coli. The results of antioxidant activity of the CSE- GQDs evaluated using DPPH scavenging assays indicate that the CSE- GQDs possess a higher scavenging activity. The germination rate of Nutmeg seeds significantly increased after treatment with higher CSE-GQDs. Our examinations develop the chance to utilize graphene quantum dots as plant development controllers that is possible to utilize in an assortment of different food plants for highly efficient.
Keywords: XRD, SAED, Anti-Cancer, Anti-Bacterial, Anti-Microbial, Plant Growth Regulators.
Scope of the Article: Biomedical Computing