Statistical Mixture Design: Study of Solvent Performance in Temperature Controlled Microwave Assisted Extraction System on Antioxidant Properties of Nephrolepis biserrata (Schott.) Sw. frond Extract
Faridah Kormin1, Muhammad Khan2, Nor Shafawati Mohd Shafie3, Azhari Hamid Nour4

1Faridah Kormin, Faculty of Science, Technology and Human Development, University Tun Hussein Onn Malaysia, Parit Raja, Batu Pahat, Johor, Malaysia.
2Muhammad Khan, Department of Genetics, Hazara University Mansehra, KPK Pakistan.
3Nor Shafawati Mohd Shafie, Faculty of Science, Technology and Human Development, University Tun Hussein Onn Malaysia Parit Raja, Batu Pahat, Johor, Malaysia.
4Azhari Hamid Nour, Faculty of Industrial Science and Technology, University Malaysia Pahang, Gambang, Pahang, Malaysia, Rosli Mohd Yunus, Faculty of Natural Resources and Chemical Engineering, University Malaysia Pahang, Gambang, Pahang.
Manuscript received on 14 December 2018 | Revised Manuscript received on 26 December 2018 | Manuscript Published on 24 January 2019 | PP: 166-171 | Volume-7 Issue-4S2 December 2018 | Retrieval Number: ES20100017519/19©BEIESP
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© The Authors. Blue Eyes Intelligence Engineering and Sciences Publication (BEIESP). This is an open access article under the CC-BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)

Abstract: Statistical simplex-centroid design mixtures of water, acetone, acetonitrile, ethanol was used to extract Nephrolepis biserrata (Schott.) SW. frond (NBF) using temperature controlled microwave extraction system (TCMES). The effects of different solvents and their mixtures on its antioxidant properties were studied. The result shows, the quality of extracted material is found to depend on the solvent proportions according to special cubic model of TPC, TFC and IC50. The binary and quaternary solvents are found to explain the superior extraction results as compared to single solvent for TPC, TFC and IC50.
Keywords: Mixture Design, Nephrolepis Biserrata (Schott.) Sw, TPC, TFC, IC50.
Scope of the Article: Microwave Filter