Antidiabetic Activity of Sida Rhombifolia (L) Leaf Extract
Lekshmi Gangadhar1, Anooj E.S2, M. Charumathy3, Vibala. B.V4

1Lekshmi Gangadhar, Xcellogen Biotech India Pvt Ltd, Nagercoil (Tamil Nadu), India.
2Anooj E.S, Xcellogen Biotech India Pvt Ltd, Nagercoil (Tamil Nadu), India.
3Dr. M. Charumathy, Assistant Professor, Department of Biochemistry, Marudhar Kesari Jain College For Women, Vaniyambadi (Tamil Nadu), India.
4Vibala. B.V, Xcellogen Biotech India Pvt Ltd, Nagercoil (Tamil Nadu), India.
Manuscript received on 11 October 2019 | Revised Manuscript received on 20 October 2019 | Manuscript Published on 02 November 2019 | PP: 726-729 | Volume-8 Issue-2S11 September 2019 | Retrieval Number: B11180982S1119/2019©BEIESP | DOI: 10.35940/ijrte.B1118.0982S1119
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Abstract: Diabetes mellitus is a metabolic disease that is a major health problem today, the prevalence of which in latest years has been rapidly increasing worldwide. It was also considered as an untreatable metabolic illness that affects about 2.8 % of the inhabitants of the world. This study was aim to analyses the quantitative and qualitative phytochemistry and antidiabetic activity of Sida rhombifolia leaf extract. Maximum scavenging activity of alpha amylase inhibition assay of different extract was observed that the ethanol exhibited comparable to the another concentration activity in the maximum activity to compare with another value in the inhibition. Glucose uptake by yeast activity of different extract was observed the ethyl acetate exhibited comparable are responsible to maximum percentage protection. Result indicated that the sida rhombifolia(L.)plant ethyl acetate extract shows 82.30% of activity was recorded the Sida rhombifolia(L.) leaf extract cum. The overall results have clearly indicated that the extract could be used as a therapeutic agent. Though further analysis is needed as clinical trials and other advanced approaches to confirm this as a safer therapeutic medicine.
Keywords: Antidiabetic, Alpha Amylase, Inhibition Assay, Glucose, Phytochemical Analysis.
Scope of the Article: Bio-Science and Bio-Technology