Detection of liver Cancer using Lab-on-Chip Based Optical Biosensor by Nano Cavity Sensing Hole
K. Srinivas Rao1, Preeta Sharan2, Anil Tiwari3
1K. Srinivas Rao, Research Scholar, Bangalore (Karnataka), India.
2Dr. Preeta Sharan, Department of E&C Engineering, The Oxford College of Engineering, Bangalore (Karnataka), India.
3Dr. Anil Tiwari, Director, Amity Tech and Engg, Bangalore (Karnataka), India.
Manuscript received on 17 December 2018 | Revised Manuscript received on 29 December 2018 | Manuscript Published on 24 January 2019 | PP: 430-434 | Volume-7 Issue-4S2 December 2018 | Retrieval Number: ES2096017518/19©BEIESP
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© The Authors. Blue Eyes Intelligence Engineering and Sciences Publication (BEIESP). This is an open access article under the CC-BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
Abstract: The paper includes the Nano cavity Implementation of the biosensor in the two stages of the cancer including the primary and the secondary. The key challenge in the work is to provide the accuracy with the sensors and the results by communicating the medical reports to the doctors or patient. By imposing the requirement to the modern development in challenging the medical aspects with the Nano Plasmon execution. The Photonic Crystal model simulation is done in the 2D model of Holes-In-Slab with change in the refractive index in selected sensing hole. The refractive index material of the normal cancer by combining the refractive index of the primary and secondary stage in order to know the tissue is cancerous or non-cancerous. Six different sensing holes are considered with six different RI Sensitivity and Quality factors for different sensing holes for different cancerous tissues are investigated. The overall quality factor obtained is 123400 µm/RIU for 1550 nm of wavelength. High quality factor is obtained from the H4 holes in the slab of nearly of 2250 and sensitivity of 0.95nm/RIU.
Keywords: Quality Factor, Biosensors, Refractive Index, Photonic Crystal, Early Stage Diagnosis.
Scope of the Article: Optical Devices