Bioengineered Zinc Oxide Nanoparticles for Anti-Oxidant Applications
Subburaman Chandramohan1, Dhanuskodi Saranya2, Krishnan Sundar3, Azhaguchamy Muthukumaran4
1Dhanuskodi Saranya, Department of Biotechnology, K.S.R Engineering College, Trichengode, (Tamil Nadu), India.
2Subburaman Chandramohan, Department of Biotechnology, Kalasalingam Academy of Research and Higher Education College, Krishnankoil (Tamil Nadu), India.
3Krishnan Sundar, Department of Biotechnology, Kalasalingam Academy of Research and Higher Education College, Krishnankoil (Tamil Nadu), India.
4Azhaguchamy Muthukumaran, Department of Biotechnology, Kalasalingam Academy of Research and Higher Education College, Krishnankoil (Tamil Nadu), India.
Manuscript received on 05 December 2019 | Revised Manuscript received on 24 December 2019 | Manuscript Published on 31 December 2019 | PP: 1003-1006 | Volume-8 Issue-4S2 December 2019 | Retrieval Number: D11451284S219/2019©BEIESP | DOI: 10.35940/ijrte.D1145.1284S219
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© The Authors. Blue Eyes Intelligence Engineering and Sciences Publication (BEIESP). This is an open access article under the CC-BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
Abstract: Zinc oxide nanoparticles find its versatile application in medicine and industry when compared with other metal nanoparticles. The present study focuses on biogenic synthesis of Zinc Oxide nanoparticles (ZnONPs) using lemon juice extract. Lemon juice extracts contains natural alkaloids and flavonoids which acts as reducing agent for the synthesis of nanoparticles. The synthesized zinc oxide nanoparticle is characterized by Scanning Electron Microscopy (SEM) and FTIR. FTIR results showed the presence of functional groups which represents ZnONPs and reducing groups responsible for the reduction. The SEM observation reveals the synthesized ZnONPs are cube shaped. The obtained nanoparticle was further studied for toxicity using zebrafish embryos. Toxicity results suggested that the toxicity is dose dependent. Malformations in the embryos such as yolk sac edema and twisted tail were seen in higher concentrations. The antioxidant activity of the synthesized ZnONPs was carried out using DPPH assay. Results implied that the antioxidant activity was also concentration dependent.
Keywords: ZnONPs, Lemon Juice Extract, Toxicity, DPPH Assay.
Scope of the Article: Bio-Science and Bio-Technology