Healing Effects of Fresh Earthworms (Pheretima Javanica K.) for Typhoid Fever Induced in Male White Rat (Rattus Norvegicus L.)
Joko Waluyo1, Dwi Wahyuni2, Wiwien S. Utami3
1Joko Waluyo, Department of Biologi Education, University of Jember, Jember, Indonesia.
2Dwi Wahyuni, Department of Biologi Education, University of Jember, Jember, Indonesia.
3Wiwien S. Utami, Department of Medical, University of Jember, Jember, Indonesia.
Manuscript received on 15 March 2019 | Revised Manuscript received on 22 March 2019 | Manuscript published on 30 July 2019 | PP: 2012-2014 | Volume-8 Issue-2, July 2019 | Retrieval Number: B2074078219/19©BEIESP | DOI: 10.35940/ijrte.B2074.078219
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© The Authors. Blue Eyes Intelligence Engineering and Sciences Publication (BEIESP). This is an open access article under the CC-BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
Abstract: Typhoid fever is systemic infectious disease caused by Salmonella typhi bacteria which is still considered as a health problem for the world people. This reasearch aims to know the healing efffects of fresh earthworm species Pheretima javanica to reduction typhoid fever replace the treatment using cloramphenicol. This research using male white rats (Rattus norvegicus L.) with negative control and positive control by using cloramphenicol. and 4 treatments group of each 5 rats. The test consists of Widal test, feces test and body weight measurement were analyzed descriptively, while body temperature measurement was analyzed by using ANOVA test and continued with Duncan test with confidence rate at 95%. The analyzed result got probably result p = 0,0001 (p < 0,05) means that fresh earthworm has a significant effect on the reduction of typhoid fever on male white rats with optimal dosage is 3 gram / 0.2 kg BB.
Index Terms: Fresh Pheretima Javanica K., Typhoid Fever, Salmonella Typhi, Widal Test.
Scope of the Article: Healthcare Informatics